Oxygen transport during hemodilution with a perfluorocarbon-based oxygen carrier: effect of altitude and hyperoxia
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چکیده
منابع مشابه
Oxygen transport during hemodilution with a perfluorocarbon-based oxygen carrier: effect of altitude and hyperoxia.
Oxygen delivery and consumption after hemodilution with a perfluorocarbon-based oxygen carrier (PFCOC) was evaluated at sea level and at 2,600 m above sea level. Fifteen anesthetized rats were subjected to a two-exchange normovolemic hemodilution of 40% of the circulating blood volume each. First exchange was performed with a colloid solution. Second exchange was with 80% PFCOC and 20% colloid....
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Previous studies have shown that increased oxygen delivery, via increased convection or arterial oxygen content, does not speed the dynamics of oxygen uptake, Vo(2m), in dog muscle electrically stimulated at a submaximal metabolic rate. However, the dynamics of transport and metabolic processes that occur within working muscle in situ is typically unavailable in this experimental setting. To in...
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The oxygen transport capacity of phospholipid vesicles encapsulating purified Hb (HbV) produced with a Po(2) at which Hb is 50% saturated (P 50 ) of 8 (HbV(8)) and 29 mmHg (HbV(29)) was investigated in the hamster chamber window model by using microvascular measurements to determine oxygen delivery during extreme hemodilution. Two isovolemic hemodilution steps were performed with 5% recombinant...
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BACKGROUND AND PURPOSE To evaluate the effects of hemodilution on cerebral hemodynamics and oxygen metabolism in the normal human brain, we measured regional cerebral blood flow, oxygen extraction fraction, oxygen metabolic rate, and regional cerebral blood volume in eight normal volunteers before and after hemodilution using positron emission tomography and oxygen-15-labeled gas inhalation tec...
متن کاملEvaluation of adherence to oxygen therapy standards before, during and after oxygen hood administration
Background and Purpose: Oxygen therapy is one of the common treatments for neonates with cardiopulmonary disease. The aim of this study was to evaluate adherence to oxygen therapy standards by nurses before, during and after using oxygen hood. Methods: In this cross-sectional study, 250 cases of nursing care were evaluated before, during and after administration of oxygen hood therapy in pre...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2008
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00152.2008